Our investigations into delocalised clinical trials
Investigations in troubled waters
Between July 2012 and June 2013, Public Eye commissioned investigations in four countries among the preferred destinations of the Swiss companies Roche and Novartis for clinical trials: Russia, Ukraine, Argentina et India. This proved to be a tedious task, performed in the climate of non-transparency that characterises drugs testing. Information is hard to come by, and the research teams – subject to confidentiality clauses – are threatened by legal proceedings if they decide to disclose information. As for the people taking part in the trials, identifying and approaching them is very difficult. However, on the basis of testimonies of key people, confidential documents and cross-checking, we were able to confirm the existence of ethical violations in all these countries. The most frequent ones were: problems in obtaining informed consent; controversial tests using placebos; discontinuation of treatment at the end of the trial; and an absence of willingness to offer compensation in case of damage to health.
These investigations have not (and probably will not) be followed up or updated. The results published on this web site are those obtained during our research in 2013.
Also in Europe, vulnerable individuals are used in clinical trials, as in Poland where Novartis tested a vaccine against avian ’flu on homeless people without obtaining their consent and while violating the rules of good clinical practice. Public Eye conducted an investigation and gathered testimonies. One participant in the clinical trial intends to file a complaint against the Basel-based company – a procedure that could represent a landmark in this area.
This investigation will be regularly updated in line with the developments in the legal process, in which Public Eye is not formally involved.
In the land of the pharaohs, the Swiss pharmas are king
In 2016, Public Eye continued its research by conducting a new investigation in Egypt. Since the “Arab Spring” of 2011, this country has suffered from severe political instability. With the ousting of the president Mohamed Morsi in a military coup d’état in 2013, the situation has worsened for those representing civil society. Freedom of the press is severely restricted, and this state of affairs is particularly worrying with regard to human rights.
This political context could have discouraged pharmaceuticals multinationals from delocalising to this country such risky and complex practices as drugs testing. However, our investigation in Egypt shows to the contrary that the pharmaceuticals industry takes advantage of loopholes in the public health system to perform clinical trials on a vulnerable population at a much lower cost. The practices are similar: gaps in the legislation; skewed consent due to lack of choice; and no guarantees as to the continuity of the treatment after the end of the trial
This research will be regularly updated in line with developments in Egypt, in particular concerning a new law on regulating clinical trials in this country (currently being discussed in the Egyptian parliament). In April 2018, the DW Arabia channel devoted a one-hour programme to this subject, with the participation of Public Eye.